The Association for the Advancement of Alternatives Assessment (A4) is a professional association solely dedicated to advancing the science, practice, and policy of alternatives assessment and informed substitution. A4 is an interdisciplinary community of researchers and practitioners from government agencies, academia, industry, and non-profits working collaboratively to accelerate the transition to the use of safer chemicals, materials, processes, and products.
The A4 includes professionals representing the broad range of scientific disciplines involved in alternatives assessment and informed substitution – toxicology, exposure science, engineering, chemistry, lifecycle assessment, law and policy, and economics, among others – who are working to advance the methodological underpinnings, best practices, and professional capacity for the field.
The vision of A4 is that every essential function performed by a chemical, material, process, or product is achieved with safe and sustainable solutions.
The mission of A4 is to enhance the science of alternatives assessment, advance informed substitution, and support a vibrant, effective community of practitioners.
The U.S. National Research Council defines alternatives assessment as a “process for identifying and comparing potential chemical and non-chemical alternatives that could replace chemicals of concern on the basis of their hazards, comparative exposure, performance, and economic viability”
The field of alternatives assessment is being driven by increasing policy and market demands to substitute chemicals of concern in process and products and the need to help decision-makers in industry and government make smarter and safer choices about the chemicals, materials and technologies used. There are two primary goals of alternatives assessment:
NRC Framework to Guide Selection of Chemical Alternatives (2014)
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There are increasing regulatory and market pressures for companies and other chemical users to replace chemicals of concern with safer, more sustainable substitutes. Alternatives assessment has evolved as a science-policy approach for systematically evaluating the pros, cons, and trade-offs associated with chemical, process, and design substitutes. While there have been important scientific and technological developments in alternatives assessment methods and tools (including hazard, exposure, performance, cost, and life cycle considerations) and their application in public and private substitution decisions, there currently is no organization that convenes the multiple disciplines involved in both the methodological development and practice of alternatives assessment and informed substitution.
Professionals building the field of alternatives assessment and informed substitution have been loosely connected through a community of practice over the last decade. However, to achieve the goal of supporting the transition to safer chemicals while minimizing unintended consequences, a more formalized community is needed to:
The A4 provides a forum for advancing sound science to support quality assessments, developing professional excellence, enhancing capacity, and sharing best practices in the field.
Learn more on membership levels and benefits.