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Alternatives Assessment Resources

OECD Substitution and Alternatives Assessment Toolbox

Includes a detailed compilation of tools, frameworks, case studies, and policies relevant to chemical substitution and alternatives assessments

OSHA Transitioning to Safer Chemicals

Contains a step-by-step framework and guide with links to resources to support companies in transitioning to safer chemicals in their firms.

Massachusetts Toxics Use Reduction Institute

Hosts a range of educational and technical resources on alternatives assessment and substitution, including databases, case studies, reports, and educational materials

Interstate Chemicals Clearinghouse

View the IC2 alternatives assessment library here.

Includes a searchable database of state chemicals policies, chemical hazard assessments, lists of chemicals of concern and the IC2 alternatives assessment guide – a comprehensive assessment framework.


European initiative that includes model tools, lists of chemicals and endpoints of concern, case studies and training resources.